Spravato - Pro Spine & Pain - Wisconsin Pain Physicians

What Is Spravato?

Spravato (esketamine) is an FDA-approved innovative treatment for patients suffering from treatment-resistant depression (TRD). Unlike traditional antidepressants, Spravato works differently by targeting the NMDA receptor in the brain, which plays a key role in regulating mood. This treatment offers new hope for individuals who have not responded to other forms of therapy or medication.

Administered as a nasal spray under medical supervision, Spravato provides rapid relief of depressive symptoms, often within hours or days, compared to the weeks it typically takes for oral antidepressants to take effect. This fast-acting nature makes it a breakthrough option for individuals in need of immediate improvement in their mental health.

How Does Spravato Work?

Spravato works by targeting glutamate, a neurotransmitter in the brain that influences mood regulation. It is believed to enhance the brain’s plasticity—its ability to form new connections—which can help reduce symptoms of depression. Unlike traditional antidepressants that primarily target serotonin, Spravato offers a unique mechanism of action, making it a valuable option for those with TRD.

Who Is a Candidate for Spravato?

Spravato is specifically designed for adults diagnosed with treatment-resistant depression, meaning they have not experienced relief from at least two different antidepressant medications. A consultation with one of our mental health specialists will determine if this treatment is right for you.

You may be a candidate if you:

Have been diagnosed with major depressive disorder (MDD) and have not responded to multiple antidepressants.
Are experiencing depressive episodes that significantly impact your quality of life.
Have no contraindications to esketamine therapy, such as certain medical conditions or medication interactions.

What to Expect During Treatment

At Pro Spine & Pain, we provide a safe and comfortable environment for Spravato administration. The treatment process includes:

Initial Consultation: A comprehensive evaluation to assess your medical history, current medications, and suitability for Spravato.
Treatment Sessions: Spravato is self-administered as a nasal spray under the direct supervision of a healthcare provider. Sessions typically last two hours, allowing time for monitoring and ensuring safety.
Observation: After administration, patients remain in our clinic for monitoring to ensure there are no adverse reactions and to provide support if needed.
Follow-Up Care: Ongoing support and monitoring of your progress to ensure the treatment is effective and adjustments are made as necessary.

For additional information visit: https://www.spravatohcp.com/patient-resources/

Would You Like More Information?

Contact our Spravato team spravato@ppwhealth.com or 262-218-6099
Or, if you would like someone to reach out to you, please provide

FAQs

How quickly does Spravato work?

Spravato can provide symptom relief within hours or days for many patients, offering a rapid improvement in mood compared to traditional antidepressants.

Is Spravato covered by insurance?

Most major insurance plans cover Spravato for eligible patients. Our team will work with you to determine coverage and assist with prior authorizations if needed.

Can I drive after a Spravato treatment session?

No, patients are advised not to drive or operate heavy machinery until the day after treatment. You must arrange for transportation following each session.

How many treatments will I need?

The initial treatment phase typically involves two sessions per week for the first four weeks, followed by a maintenance phase with less frequent sessions. Your provider will develop a schedule tailored to your needs.